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Fluorodeoxyglucose (FDG) activity, as visualized through Positron Emission Tomography (PET) scans, reveals metabolic activity within the body. FDG, a glucose analog, is absorbed by cells that require glucose for energy. Areas of increased FDG uptake generally indicate heightened metabolic demand. For example, cancerous tumors often exhibit significantly elevated FDG uptake due to their rapid growth and energy consumption. A PET scan identifies and displays the spatial distribution and intensity of this uptake.

The assessment of metabolic activity is crucial in various clinical contexts. It allows for the detection, staging, and monitoring of diseases, particularly cancer. Observing the metabolic response to therapies, such as chemotherapy or radiation, provides invaluable insights into treatment efficacy and informs clinical decision-making. Historically, the capacity to visualize metabolic processes in vivo represented a significant advancement over relying solely on anatomical imaging.